Conferences Abstracts
2017
- Houdaihed L., Evans J., Allen C. Delivery of Paclitaxel and Everolimus in HER2-Targeted Polymeric Nanoparticles to HER2 Positive Metastatic Breast Cancer. ICONAN, International Conference on Nanomedicine and Nanobiotechnology (Sep 2017).
- Houdaihed L., Allen C. Delivery of Paclitaxel and Everolimus in Polymeric Nanoparticles to Trastuzumab Resistant HER2+ Metastatic Breast Cancer Cells. CSC, Canadian Society for Chemistry (May 2017).
- Houdaihed L., Allen C. Delivery of Paclitaxel and Everolimus in Polymeric Nano Drug Delivery System to Trastuzumab Resistant HER2+ Metastatic Breast Cancer Cells. NanoDDS, 14th International Nanomedicine & Drug Delivery Symposium (September 2016).
- Her S., Cui L., Jaffray D.A., Bristow R.G., Allen C. Cispatin-Conjugated Gold Nanoparticles as a Radiosensitizer for Treatment of Triple Negative Breast Cancer. CRS, 43rd Annual Meeting & Exposition of the Controlled Release Society (July 2016).
- Dou Y., Chaudary N., Dunne M., Huang H., Jaffray D., Milosevic M., Allen C. Heterogeneity in Cervical Tumor Microenvironment Significantly Impacts the Delivery of a Heat-Activated Thermosensitive Liposome Formulation of Cisplatin. CRS, 43rd Annual Meeting & Exposition of the Controlled Release Society (July 2016).
- Dou Y., Dunne M., Huang H., Mckee T., Jaffray D., Allen C. Hyperthermia-Induced Triggered Release of Cisplatin from Thermosensitive Liposomes and Changes in Tumor Microenvironment in Non-Small Cell Lung Carcinoma. CRS, 43rd Annual Meeting & Exposition of the Controlled Release Society (July 2016).
- Dunne M., Dou Y., Gontijo S.M.L., Spence T., Allen C. Heat-Triggered Release of Cisplatin from Thermosensitive Liposomes Improves Drug Efficacy in Models of Human Triple Negative Breast Cancer. CRS, 43rd Annual Meeting & Exposition of the Controlled Release Society (July 2016).
- Her S., Cui L., Jaffray D.A., Bristow R.G., Allen C. Cispatin-Conjugated Gold Nanoparticles as a Radiosensitizer for Treatment of Triple Negative Breast Cancer. NanoDDS, 13th International Nanomedicine & Drug Delivery Symposium (September 2015).
- Dunne M., Dou Y., Gontijo S.M.L., Spence T., Allen C. Heat-Triggered Release of Cisplatin from Thermosensitive Liposomes Improves Drug Efficacy in Models of Human Triple Negative Breast Cancer. ESHO / The European Society for Hyperthermic Oncology (June 2015).
- Dou Y.N., Chaudary N., Dunne M., Jaffray D.A., Milosevic M., Allen C. The Impact of Tumor Microenvironment on Delivery of a Heat-Activated Thermosensitive Liposome Formulation of Cisplatin for Treatment of Cervical Cancer. ESHO / The European Society for Hyperthermic Oncology (June 2015).
- Dou Y.N., Chaudary N., Dunne M., Jaffray D.A., Milosevic M., Allen C. The Impact of Tumor Microenvironment on Delivery of a Heat-Activated Thermosensitive Liposome Formulation of Cisplatin for Treatment of Cervical Cancer. AAPS Annual Meeting & Exposition (June 2015).
- Her S., Cui L., Jaffray D.A., Allen C. Cispatin-Conjugated Gold Nanoparticles as a Radiosensitizer for Treatment of Triple Negative Breast Cancer. International Congress of Radiation Research (May 2015).
- Ekdawi S.N., Stewart J.M.P., Dunne M., Stapleton S., Misakakis N., Dou Y.N., Jaffray D.A., Allen C. Determinants of Liposome Distribution at the Bulk and Intratumoral Levels: Impact of Time, Region and Vascular Density in an Orthotopic Tumor Model. Canadian Society for Pharmaceutical Sciences Symposium (May 2015).
# Recipient of Poster Award, Canadian Chapter-CRS. - Dunne M., Dou Y., Gontijo S.M.L., Spence T., Allen C. Heat-Triggered Release of Cisplatin from Thermosensitive Liposomes Improves Drug Efficacy in Models of Human Triple Negative Breast Cancer. Canadian Society for Pharmaceutical Sciences Symposium (May 2015).
# Recipient of Poster Award, Canadian Chapter-CRS. - Dou Y.N., Chaudary N., Dunne M., Jaffray D.A., Milosevic M., Allen C. The Impact of Tumor Microenvironment on Delivery of a Heat-Activated Thermosensitive Liposome Formulation of Cisplatin for Treatment of Cervical Cancer. Canadian Society for Pharmaceutical Sciences Symposium (May 2015).
- Le Devedec F., Jeginovic D., Houdaheid L., Allen C. Synthesis and Characterization of Functional Block Copolymers Obtained by Living Anionic Polymerization for Delivery of Cisplatin. Canadian Society for Pharmaceutical Sciences Symposium (May 2015).
- Le Devedec F., Oake J, Wong A, Houdaihed L, Yip C, Bohne C, Allen C. Design of Block Copolymer Micelle-Based Drug Formulations using AB Copolymers Synthesized by Living Anionic Polymerization : Effect of Pendant Functional Groups on the Aggregation Behaviour and the Drug Retention. Canadian Society for Pharmaceutical Sciences Symposium (May 2015).
- Ekdawi S.N., Stewart J.M.P., Dunne M., Stapleton S., Jaffray D.A., Allen C. Spatial and Temporal Mapping of Heterogeneity in Liposome Uptake and Microvascular Distribution in an Orthotopic Tumor Xenograft Model. European Molecular Imaging Meeting (March 2015).
# Shortlisted for Young Investigator Award.
- De Souza R., Zheng J., Serra S., Francia G., Kerbel R., Allen C., Jaffray D. Multimodal Imaging-Based Characterization of HER2+ and Triple Negative Metastatic Breast Cancer Xenograft Models in Mice. Annual Meeting & Exposition of the Controlled Release Society(July 2014).
- Dou Y., Zheng J., Weersink R., Chaudary N., Foltz W.D., Jaffray D.A., Allen C. Use of Heat-activated Thermosensitive Liposomes of Cisplatin (HTLC) for the Treatment Cervical Carcinoma. Canadian Society of Pharmaceutical Sciences 17th Annual Symposium (June 2014). # Recipient of 2014 Gattefossé Canada/CSPS Award in Lipid-Based Drug Delivery.
- Dou Y., Zheng J., Foltz W.D., Weersink R., Chaudary N., Milosevic M., Jaffray D.A., Allen C. MR Image-guided Delivery of Cisplatin in Thermosensitive Liposomes (HTLC) Results in Effective Growth Delay in Numerous Xenograft Models of Human Cervical Cancer.AAPS Annual Meeting & Exposition (Nov 2014). # Recipient of 2014 AAPS Graduate Student Research Award in Formulation Design and Development.
- Ekdawi S.N., Stewart J.M.P., Dunne M., Dou YN., Jaffray D.A., Allen C. Spatio-Temporal Distribution of a Stable, CT/Optical Liposome Formulation at the Whole Body and Intratumoral Levels. European Symposium on Controlled Drug Delivery (April 2014).
- Cui L., Tse K., Zahedi P., Harding S.H., Zafarana G., Jaffray D.A., Bristow R.G., Allen C.Cellular Localization and Hypoxia Influence the Radiosensitizing Effect of Gold Nanoparticles (AuNPs) in Breast Cancer Cells. 59th Annual Meeting of the Radiation Research Society (September 2013).
- Zheng J., Muhanna N., De Souza R., Li M., Akens M., Daly M., Chan H., Dunne M., Wada H., Yasufuku K., Irish J., Allen C., Jaffray D.A. Image-guided Surgery with a Dual-modality CT and NIR Fluorescence Nano-agent. World Molecular Imaging Congress(September 2013).
- Zheng J., Coulthard T., Ahmed S., Zair M., Ghanekar A., Allen C., Jaffray D.A. Dual-modality CT/MR Agent for Image-guided Radiotherapy of Liver Tumors. World Molecular Imaging Congress (September 2013).
- De Souza R., Zheng J., Dunne M., Kerbel R.S., Allen C., Jaffray D.A. Multimodality imaging-based Characterization of a Xenograft Model of Metastatic Breast Cancer in Mice. World Molecular Imaging Congress (September 2013).
- Zheng J., De Souza R., Li M., Dunne M., Allen C., Jaffray D.A. CT/Optical Liposomes for High Accuracy Tumor Resection Using Image-Guided Surgery. 40th Annual Controlled Release Society Meeting and Exposition (July 2013).
- Eetezadi S., Mikhail A.S., Allen C. Multicellular Tumor Spheroids for Performance Evaluation of Nanomedicines In Vitro. 40th Annual Controlled Release Society Meeting and Exposition (July 2013).
- Dou Y., Zheng J., Weersink R., Chaudary N., Foltz W.D., Jaffray D.A., Allen C. Heat-activated Thermosensitive Liposomal Cisplatin (HTLC) Results in Effective Growth Delay of Cervical Carcinoma in Mice. 40th Annual Controlled Release Society Meeting and Exposition (July 2013).
- Zheng J., Muhanna N., De Souza R., Li M., Akens M., Daly M., Chan H., Dunne M., Wada H., Yasufuku K., Irish J., Allen C., Jaffray D.A. A Multimodal CT/Optical Agent for Image-Guided Surgery. European Molecular Imaging Meeting (May 2013).
# Short-listed for Young Investigator Award. - Banerjee N., Fonge H., Mikhail A., Reilly R., Allen C., Bendayan R. Estrone- 3-sulphate, A Potential Ligand for Targeting Breast Cancers. American Association for Cancer Research Annual Meeting (April 2013).
- Zheng J., Fan L., Dou Y., Allen C., Jaffray D. 64-Cu-Iodine Liposomes for High Sensitivity and High Resolution PET/CT Imaging of Nanoparticle Distribution in Orthotopic Cervical Tumors. World Molecular Imaging Congress (September 2012).
- Green D.E., Huang H., Dunne M., Zheng J., Vines D., Allen C., Jaffray D.A. A Dual Modality Liposome Formulation for the In vivo Assessment of Tumor Uptake Using Quantitative PET/CT Imaging. World Molecular Imaging Congress (September 2012).
- Ekdawi S., Stewart J., Dunne M., Theyers A., Zheng J., Dou Y., Jaffray D.A., Allen C.Quantitative Assessment of the Intratumoral Distribution of APN/CD13-Targeted Liposomes in Cervical Cancer. World Molecular Imaging Congress (September 2012).
- Dunne M., Anayama T., Driscoll B., Nakajima T., Fan L., Zheng J., Coolens C., Keshavjee S., Yasufuku K., Allen C., Jaffray D.A. A Multimodal CT/Optical Imaging Agent for Improved Lung Cancer Detection. World Molecular Imaging Congress (September 2012).
- Lee H., Zheng J., Gaddy D., Kirpotin D., Dunne M., Allen C., Jaffray D.A., Hendriks B., Wikham T. MM-Dx-929; A Novel Cu-64-Liposomal PET Agent for Predicting Antitumor Treatment Response to Immunoliposomal Chemotherapeutics. World Molecular Imaging Congress (September 2012).
- Gaddy D., Lee H., Zheng J., Dunne M., Drummond D., Allen C., Jaffray D.A., Hendriks B., Wikham T., Kirpotin D. Preclinical Development of MM-DX-929, a Novel Liposomal PET-Based Radiopharmaceutical Imaging Contrast Agent. World Molecular Imaging Congress (September 2012).
- Mikhail A., Eetezadi S., Stewart J., Allen C. Multicellular Tumor Spheroids for the Evaluation of Nanoparticle Intratumoral Transport. 39th Annual Controlled Release Society Meeting and Exposition (July 2012).
# Recipient of Best Poster Award, Canadian Chapter-CRS. - Stapleton S., Milosevic M., Allen C., Jaffray D.A. A Biophysical Transport Model to Predict the Enhanced Permeability and Retention Effect for Liposome Accumulation in Solid Tumors. 39th Annual Controlled Release Society Meeting and Exposition (July 2012).
- Banerjee N., Fonge H., Allen C., Bendayan R. Organic Anion Transporting Polypeptides (OATPs): A New Molecular Target for Hormone Dependent Breast Cancers. Canadian Society for Pharmaceutical Sciences 2012 Annual Symposium (June 2012).
- Banerjee N., Allen C., Bendayan R. Organic Anion Transporting Polypeptides (OATPs): A New Molecular Target for Hormone Dependent Breast Cancers. Association of Faculties of Pharmacy of Canada (AFPC) Annual Conference (June 2012).
# Awarded AFPC – Rx and D Pharmacy Student Research Poster Award and nominated for AFPC-Whit Matthews Graduate / Undergraduate Student Poster Award). - Banerjee N., Fonge H., Allen C., Bendayan R. Organic Anion Transporting Polypeptides (OATPs): A New Molecular Target for Hormone Dependent Breast Cancers. American Association for Cancer Research Annual Meeting (April 2012).
- Huynh L., Neale C., Pomès R., Allen C. Rational Design of Unimolecular Star Copolymer Micelles for Drug Delivery: Molecular Dynamics Study of Solvation, Aggregation, and Drug Binding Properties. Biophysical Society (March 2011).
- Stapleton S., Dunne M., Chaudary N., Allen C., Jaffray D.A. A biophysical transport model for predicting the passive retention of liposomes in solid tumors. 9th Annual Imaging Network Ontario Symposium (February 2011).
- Huynh L. , Leroux J.-C., Allen C. Enhancement of Docetaxel Solubility via Conjugation of Formulation-Compatible Moieties. AAPS Annual Meeting and Exposition (November 2010).
- Huynh L., Neale C., Pomès R., and Allen C. Systematic Design of Unimolecular Star Copolymer Micelles Using Molecular Dynamics Simulations. AAPS Annual Meeting and Exposition (November 2010).
- Zahedi P., De Souza R., Piquette-Miller M., Allen C. Continuous and Localized Delivery of Docetaxel via a Polymer-Lipid Formulation for the Treatment of Ovarian Cancer. AAPS Annual Meeting and Exposition (November 2010).
- Zahedi P., Huynh L., De Souza R., Piquette-Miller M., Allen C. A Combination Drug Delivery Strategy to Overcome Multi-Drug Resistance in Ovarian Cancer. AAPS Annual Meeting and Exposition (November 2010).
- Zahedi P., De Souza R., Piquette-Miller M., Allen C. Continuous and Localized Delivery of Docetaxel via a Polymer-Lipid Formulation for the Treatment of Ovarian Cancer.NanoDDS (October 2010).
- Zahedi P., Huynh L., De Souza R., Piquette-Miller M., Allen C. A Combination Drug Delivery Strategy to Overcome Multi-Drug Resistance in Ovarian Cancer. NanoDDS(October 2010).
- Huynh L., Leroux J.-C., Allen C. Enhancement of Docetaxel Solubility via Conjugation of Formulation-Compatible Moieties. Canadian Society of Chemistry Conference (June 2010).
- Stapleton S., Dunne M., Chaudary N., Allen C., Jaffray D.A. A biophysical transport model for predicting targeted macromolecule retention in solid tumors. 12th International Tumor Microenvironment Workshop (May 2010).
- Dunne M., Zheng J., Jaffray D.A., Allen C. APN/CD13-Targeting of a Long Circulating Contrast Agent in Non-Small Cell Lung Cancer. Terry Fox Research Institute 2nd Annual Scientific Meeting (May 2010).
- De Souza R., Zahedi P., Allen C., Piquette-Miller M. Therapeutic advantages of continuous chemotherapy in the treatment of advanced epithelial ovarian cancer. 5th Canadian Conference on Ovarian Cancer Research (May 2010).
# Recipient of Best Poster Award. - Stapleton S., Dunne M., Chaudary N., Allen C., Jaffray D.A. Quantifying Microenvironment Properties which Affect the Transport of Macromolecules in Solid Tumours. 2nd annual Terry Fox Research Institute Scientific Meeting (May 2010).
- Huynh L., Neale C., Pomes R., Allen C. Systematic design of unimolecular star copolymer micelles using molecular dynamics simulations. Chemical Biophysics Symposium (April 2010).
- Mikhail A., Allen C. Development of a Polymer-Drug Conjugate Based Micelle System for the Delivery of Docetaxel for Cancer Therapy. Symposium on Biomedical Polymers for Drug Delivery (March 2010).
- Zheng J., Allen C., Jaffray D.A. CT/MR Contrast Agent for Longitudinal Localization and Delineation of Target Structures in Image-Guided Radiotherapy. Molecular Imaging in Radiation Oncology (March 2010).
- De Souza R., Zahedi P., Moriyama E.H., Allen C., Wilson B.C., Piquette-Miller M. Efficacy of an injectable polymer-lipid implant for sustained and localized delivery of docetaxel in a murine xenograft model of human ovarian cancer. AAPS Annual Meeting and Exposition (November 2009).
- Zheng J., Allen C., Serra S., Vines D., Charron M., Jaffray D.A. Liposome Contrast Agent for CT-based Detection and Localization of Neoplastic and Inflammatory Lesions in Rabbits: Validation with FDG-PET and Histology. World Molecular Imaging Congress(September 2009).
- Huynh L., Neale C., Pomes R., Allen C. Optimization of poly(ethylene glycol)-blockpolycaprolactone Star Copolymers for Rational Design of Enhanced Drug Delivery Nanomaterial Using Molecular Dynamics Simulation. American Chemical Society Meeting(August 2009).
- Zheng J., Allen C., Jaffray D.A. CT Detection of Primary and Metastatic Lesions with a Nano-Agent in Rabbits: Validation with FDG-PET. American Association of Physicists in Medicine 51st Annual Meeting (July 2009).
- Fonge H., Lee H., Reilly R.M., Allen C. Multifunctional block copolymer micelle for enhanced delivery of 111In- to EGFR positive breast cancer cells for targeted Auger electron radiotherapy. Society Nuclear Medicine 56th Annual Meeting (June 2009).
- Dunne M., Zheng J., Jaffray D.A., Allen C. An in vivo evaluation of an APN/CD13-targeted CT contrast agent. Canadian Society for Pharmaceutical Sciences 12th Annual Meeting & Symposium (June 2009).
- Zahedi P., De Souza R., Piquette-Miller M., Allen C. An Injectable Chitosan-Phospholipid Blend for Sustained and Localized Delivery of Docetaxel. Canadian Society for Pharmaceutical Sciences 12th Annual Meeting & Symposium (June 2009).
- Huang H., Lo J., Zheng J., Jaffray D., Allen C. CT/optical Imaging of Lung Cancer using Liposome-based Multimodal Probes. Canadian Society for Pharmaceutical Sciences 12th Annual Meeting & Symposium (June 2009).
- De Souza R., Zahedi P., Allen C., Piquette-Miller M. Biocompatibility and In Vitro Efficacy of Injectable Polymer-Lipid Blends For Localized Taxane Delivery. Canadian Society for Pharmaceutical Sciences 12th Annual Meeting & Symposium (June 2009).
- Zheng J., Vines D., Allen C., Jaffray D.A. Primary and Metastatic Tumor Targeting with a Novel CT Contrast Agent: Validation with FDG-PET. 4th International Conference on Translational Research and Pre-Clinical Strategies in Radiation Oncology (March 2009).
- Zheng J., Allen C., Jaffray D.A. Multimodal Nanoparticle for Tumor Characterization. Hot Topics in Molecular Imaging 2009 – Dual and Innovative Imaging Modalities (January 2009).
- Huynh L., Neale C., Pomès R., Allen C. A Molecular Dynamics Simulations Approach for Predicting Structure and Packing of Star Copolymers in Aqueous Media. 6th International Nanomedicine and Drug Delivery Symposium (October 2008).
- Hoang B., Lee H., Reilly R., Allen C. Pharmacokinetics, Biodistribution, and NanoSPECT/CT Imaging of 111In-labeled Block Copolymer Micelles in Healthy and Tumor Bearing Mice. 6th International Nanomedicine and Drug Delivery Symposium (Oct 2008).
- Dunne M., Zheng J., Jaffray D.A., Allen C. MicroCT Imaging of Non-Small Cell Lung Cancer (NSCLC) by Targeting Angiogenic Vasculature.6th International Nanomedicine and Drug Delivery Symposium (October 2008).
- Zheng J., Jaffray D.A., Allen C. Imageable Liposomes as a Tool for Improved Characterization of Nanomedicines in Preclinical Models. 6th International Nanomedicine and Drug Delivery Symposium (October 2008).
- De Souza R., Zahedi P., Lim Soo P., Allen C., Piquette-Miller M. In Vitro and In Vivo Evaluation of a Novel Injectable Polymer-Lipid Drug Implant. 6th International Nanomedicine and Drug Delivery Symposium (October 2008).
# Recipient of Poster Award. - Lee H., Hoang B., Reilly R.M., Allen C. Investigation of in vitro and in vivo Fate of Nanocarriers using 111In-Labeled Block Copolymer Micelles. 6th International Nanomedicine and Drug Delivery Symposium (October 2008).
# Recipient of Poster Award. - Dunne M., Zheng J., Jaffray D.A., Allen C. MicroCT Imaging of Lung Cancer in Mice by Targeting Aminopeptidase N. 7th Imaging Network Ontario Annual Symposium (October 2008).
- Zheng J., Dunne M., Lo J., Green D., Allen C., Jaffray D.A. Modular Imaging Platform for Disease Characterization and Therapy Guidance. 7th Imaging Network Ontario Annual Symposium (October 2008).
- Chithrani B.D., Jelveh S., Jalali F., van Prooijen M., Chow J., Allen C., Bristow R., Hill R.P., Jaffray D.A. Radiosensitization Effects of Citrate-Stabilized Gold Nanoparticles.ASTRO (September 2008).
- Dunne M., Zheng J., Jaffray D.A., Allen C. Micro-CT Imaging of Angiogenesis in Non-Small Cell Lung Cancer (NSCLC) by Tumor Vasculature Targeting. World Molecular Imaging Congress (September 2008).
- Zheng J., Allen C., Jaffray D.A. Metastases Detection with an EPR Targeting CT Contrast Agent. World Molecular Imaging Congress (September 2008).
- Hoang B., Lee H., Reilly R.M., Allen C. Rational Design, Synthesis, and Validation of 111Indium-labeled Block Copolymer Micelle Platform for Amplified nanoSPECT/CT Imaging Applications. World Molecular Imaging Congress (September 2008).
- Zheng J., Allen C., Jaffray D.A. Comprehensive Quantification of Liposome Biodistribution Using Computed Tomography in Tumor-Bearing Rabbits. World Molecular Imaging Congress (September 2008).
- Lee H., Hoang B., Reilly R.M., Allen C. Application of 111In-labeled Micelles in Molecular Imaging of EGFR-Overexpressed Cancer. World Molecular Imaging Congress(September 2008).
# Recipient of WMIC travel award. - Green D., Dunne M., Zheng J., Vines D., Hoisak J.D., Allen C., Jaffray D.A. Lipid Chelator for Longitudinal PET Imaging of Nanoparticles with Cu-64. World Molecular Imaging Congress (September 2008).
- Lee H., Hoang B., Reilly R.M., Allen C. Investigation of in vitro and in vivo Fate of Nanocarriers using 111In-Labeled Block Copolymer Micelles. Imaging Network Ontario - 7th Imaging Symposium (September 2008).
- Zheng J., Allen C., Jaffray D.A. Prolonged Discrimination of Target Structures in CT and MR-Guided Therapies Using a Novel Contrast Agent. American Association of Physicists in Medicine 50th Annual Meeting (August 2008).
- De Souza R., Zahedi P., Lim Soo P., Allen C., Piquette-Miller M. In Vitro and In Vivo Evaluation of a Novel Injectable Polymer-Lipid Drug Implant System. IXth World Conference on Clinical Pharmacology and Therapeutics (July 2008).
- Chithrani B.D., Stewart J., Allen C., Jaffray D.A. Intracellular processing and transport of nanostructures in breast cancer cells. Nanoscience and Nanotechnology Conference(February 2008).
- Lee H., Hu M., Reilly R.M., Allen C. Apoptotic Nanomedicine as a Targeted Combination Therapy for EGFR-Overexpressed Breast Cancer. Making Connections: A Canadian Cancer Research Conference Celebrating NCIC's 60th Anniversary (November 2007).
- Zahedi P., Liu J., , Zeng F., Allen C. Nano-sized Assemblies of a PEG-Docetaxel Conjugate as a Formulation Strategy for Docetaxel. Making Connections: A Canadian Cancer Research Conference Celebrating NCIC's 60th Anniversary (November 2007).
- Lee H., Hu M., Reilly R.M., Allen C. Apoptotic Nanomedicine as a Targeted Combination Therapy for EGFR-Overexpressed Breast Cancer. 5th International Nanomedicine and Drug Delivery Symposium (November 2007).
- Zheng J., Jaffray D.A., Allen C. Imaging-Based Characterization of the Enhanced Permeation and Retention (EPR) Effect of Liposomes in Tumors of Varying Aggressiveness. 5th International Nanomedicine and Drug Delivery Symposium(November 2007).
- Huynh L., Delmas P., Leroux J.C., Allen C. Use of Molecular Dynamics Simulations to Select Suitable Excipients for Formulation of the Anti-Cancer Agent Docetaxel. 5th International Nanomedicine and Drug Delivery Symposium (November 2007).
- Zheng J., Allen C., Jaffray D.A. Disease Characterization Through Distribution Kinetics of a Nano-Sized CT and MR Imaging Agent. Academy of Molecular Imaging and Society of Molecular Imaging Joint Meeting (September 2007).
- Zheng J., Green D., Allen C., Jaffray D.A. Modular Kit for Multimodality CT, MR, PET and SPECT Imaging. Academy of Molecular Imaging and Society of Molecular Imaging Joint Meeting (September 2007).
- Zheng J., Allen C., Jaffray D.A. CT and MR-Based Quantification of the Transport of Nano-encapsulated Contrast Agents Through Abnormal Vasculature in Tumors. European Society for Molecular Imaging – 2nd International Conference (June 2007).
- Zheng J., Hoisak J., Jaffray D.A., Allen C. Non-Invasive Imaging-Based Assessment of the Heterogeneous Intratumoral Distribution of Liposomes. Canadian Society of Pharmaceutical Sciences 10th Annual Symposium (May 2007).
- Huynh L., Delmas P., Leroux J.C., Allen C. Predicting the Solubility of the Anti-Cancer Drug Docetaxel in Pharmaceutical Excipients using Computational Methods. Chemical Biophysics Symposium (April 2007).
- Huynh L., Delmas P., Leroux J.C., Allen C. Molecular dynamics simulation for predicting the solubility of the anticancer drug docetaxel in pharmaceutical excipient. 233rd American Chemical Society National Meeting (March 2007).
- Cho J., Allen C. Synthesis of a water-soluble chitosan derivative: Reaction kinetics and mechanism. 233rd American Chemical Society National Meeting (March 2007).
- Lim Soo P., Grant J., Mak M., Piquette-Miller M., Allen C. In vitro release and in vivo biodistribution of paclitaxel from a chitosan-egg phosphatidylcholine implant system.233rd American Chemical Society National Meeting (March 2007).
- Zheng J., Hoisak J., Allen C., Jaffray D.A. Longitudinal Vascular Imaging Using a Novel Nano- Encapsulated CT and MR Contrast Agent. International Society of Optical Engineering (SPIE) Medical Imaging (February 2007).
# Finalist in the Michael B. Merickel Best Student Paper Competition.
- Zheng J., Jaffray D.A., Allen C.In Vivo Tracking of Liposomes Using CT and MR Imaging.BioContact Quebec (October 2006).
# Recipient of 3rd Prize in CIHR Next Generation Award Competition. - Lee H., Dunne M., Zeng F., Allen C. EGF-Conjugated Block Copolymer Micelles: Drug Carriers for Targeted Delivery of Chemotherapeutic Agent and Apoptotic Factor to EGFR-overexpressed Breast Cancer. Gordon Research Conferences 2006 - Drug Carriers in Medicine & Biology (August 2006).
- Vassileva V., Grant J., Allen C., Piquette-Miller M. Novel Drug Delivery System for Paclitaxel Increases Tolerability and Therapeutic Efficacy in a Human Ovarian Cancer Model. Great Lakes Symposium on Pharmaceutical Sciences (July 2006).
# Recipient of the Best Podium Presentation Award. - Zheng J., Dunne M., Allen C., Jaffray D. Performance of CT and MR-based Assays for In Vivo Agent Concentration Quantitation. American Association of Physicists in Medicine 48th Annual Meeting (July 2006).
- Ho E., Lim Soo P., Allen C., Piquette-Miller M. Sustained Intraperitoneal Delivery of Paclitaxel on the Regulation of P-glycoprotein in Ovarian Tumors. Canadian Society of Clinical Pharmacology (May 2006).
# Selected for Trainee Oral Presentation. - Zheng J., Dunne M., Allen C., Jaffray D. Multimodal Contrast Agent for Combined CT and MR Imaging. Canadian Organization of Medical Physicists Annual Meeting and the Canadian College of Physicists in Medicine Symposium (May 2006).
# Recipient of the Best Oral Presentation Award. - Ho E., Lim Soo P., Allen C., Piquette-Miller M. Sustained Intraperitoneal Delivery of Paclitaxel on the Regulation of P-Glycoprotein in Ovarian Tumours. 3rd National Conference on Ovarian Cancer Research (May 2006).
# Recipient of NCIC Student Travel Award. - Zheng J., Liu, J., Jaffray D., Allen C. In vivo tracking of liposomes using CT and MR imaging. 9th Annual NSTI Nanotechnology Conference and Trade Show (May 2006).
- Zheng J., Dunne M., Jaffray D., Allen C. Non-invasive Assessment of the In Vivo Pharmacokinetics of Liposomes Using CT and MR Imaging. Canadian Society of Pharmaceutical Sciences 9th Annual Symposium (May 2006).
- Lee H., Zeng F., Allen C. Development of EGF-Conjugated Block Copolymers Micelles for Actively Targeted Drug Delivery to EGFR-Overexpressed Cancers. Canadian Society of Pharmaceutical Sciences (CSPS) 9th Annual Symposium (May 2006).
- Grant J., Vassileva V., Piquette-Miller M., Allen C. Biological and Mechanical Evaluation of a Polymer-Lipid Blend for Drug Delivery. Canadian Society of Pharmaceutical Sciences 9th Annual Symposium. (May 2006).
# Recipient of Gattefosse Lipid Research Award. - Liu J., Zeng F., Allen C. Pharmacokinetics and Biodistribution Profiles of the Micelle Forming Block Copolymer Poly(ethylene glycol)-block-Poly(caprolactone) Following Systemic Administration. Canadian Society of Pharmaceutical Sciences 9th Annual Symposium (May 2006). # Recipient of Biovail Contract Research Award of Excellence.
- Vassileva V., Grant J., Allen C., Piquette-Miller M. Novel Drug Delivery System for Paclitaxel Increases Tolerabilty and Therapeutic Efficacy in a Human Ovarian Cancer Model. Canadian Society for Clinical Pharmacology 3rd Annual Therapeutics Congress(May 2006).
- Vassileva V., Grant J., Allen C., Piquette-Miller M. Novel Drug Delivery System for Paclitaxel Increases Tolerabilty and Therapeutic Efficacy in a Human Ovarian Cancer Model. Women's Health Research: From Cell to Society (May 2006).
- Liu J., Zeng F., Allen C. In Vivo Fate of Poly (ethylene glycol)-block-Poly(caprolactone) Copolymer Unimers and Micelles in Mice Following Intravenous Administration. 9th Annual Symposium of the Canadian Society of Pharmaceutical Sciences ( May 2006).
# Recipient of "Biovail Contract Research Award of Excellence". - Liu J., Zeng F., Allen C. In vivo fate of a micelle forming copolymer poly (ethylene glycol)-block-poly (caprolactone) in mice following intravenous administration. The Particle 2006 Conference (April 2006).
- Grant J., Tomba J.P., Lee H., Allen C. Composition-Property Relationships of Chitosan-Egg Phosphatidylcholine Films for Use in Drug Delivery. Society for Biomaterials 2006 Annual Meeting (April 2006).
- Ho E., Lim Soo P., Allen C., Piquette-Miller M. Impact of Localized, Sustained Delivery of Paclitaxel on the in Vitro and in Vivo Regulation of P-Glycoprotein. American Society for Clinical Pharmacology and Therapeutics Annual Meeting (March 2006).
- Zheng J., Allen C., Jaffray D. Multimodal Contrast Agent for Radiation Therapy Planning and Guidance. 3rd International Conference on Translational Research and Pre-Clinical Strategies in Radiation Oncology (March 2006).
- Ho E., Allen C., Piquette-Miller M. Preclinical Evaluation of a Novel 2-in-1 Drug Delivery Strategy for the Treatment of Ovarian Cancer. BioContact (October 2005).
# Recipient of Biocontact/CIHR Student Award. - Liu J., Lee H., Huesca M., Allen C. Physico-chemical Characterization and Biological Evaluation of a Lipid-Based Formulation of a Hydrophobic Anti-Cancer Agent. 3rd International Nanomedicine and Drug Delivery Symposium (September 2005).
# Recipient of Travel Award. - Liu J., Zeng F., Allen C. Influence of Serum Protein on Polycarbonate-Based Copolymer Micelles as a Systemic Delivery System for Hydrophobic Anti-cancer Agent. 3rd International Nanomedicine and Drug Delivery Symposium (September 2005).
# Recipient of Travel Award. - Liu J., Zeng F., Lee H., Allen C. Nanoengineering Block Copolymer Micelles for Delivery of Hydrophobic Drugs. RSC/KAST Bilateral Symposium on Drug Delivery (July 2005).
- Zheng J., Allen C., Jaffray D. In vitro stability of a liposome-based multimodal contrast agent: a CT and MR imaging study. American Association of Physicists in Medicine 47th Annual Meeting (July 2005).
- Hoisak J., Zheng J., Perkins G., Brock K., Allen C., Jaffray D. Mutual Information as a Metric of Multimodality Contrast Agent Efficacy. American Association of Physicists in Medicine 47th Annual Meeting (July 2005).
- Vassileva V., Grant J., Allen C., Piquette-Miller M. Utilization of Novel Implantable Delivery System for the Increase of Maximum Tolerable Doses of Paclitaxel. Great Lakes Symposium on Pharmaceutical Sciences (July 2005).
- Zheng J., Perkins G., Jaffray D., Allen C. Nanoengineered Liposome-Based Multimodal Contrast Agent For Computed Tomography And Magnetic Resonance Imaging. Great Lakes Symposium on Pharmaceutical Sciences (July 2005).
# Recipient of the Best Poster Presentation Award. - Vassileva V., Grant J., Allen C., Piquette-Miller M. Novel Implantable Delivery System Increases Maximum Tolerable Doses of Paclitaxel in Mice. Association of Faculties of Pharmacy of Canada Annual Conference (June 2005).
# Recipient of Best Poster Award. - Zeng F., Lee H., Allen C. Polymeric Nanomicelles Formed from Six-Arm Star Poly(d-valerolactone)-b-Methoxy-Poly(ethylene glycol) Copolymers. 32nd Annual Meeting & Exposition of the Controlled Release Society (June 2005).
# Recipient of PostDoc Travel Award. - Zeng F., Lee H., Liu J., Allen C. EGF-Conjugated Poly(ethylene glycol)-block-Poly(d-valerolactone) Micelles as a Delivery System for Active Targeting of Hydrophobic Anticancer Agents. 32nd Annual Meeting & Exposition of the Controlled Release Society(June 2005).
# Recipient of Highlights of Student Posters. - Vassileva V., Grant J., Allen C., Piquette-Miller M. Novel Implantable Delivery System Increases Maximum Tolerable Doses of Paclitaxel in Mice. Women's Health Research: From Cell to Society (May 2005).
# Recipient of Best Oral Presentation Award. - Zheng J., Perkins G., Jaffray D., Allen C. Nanoengineered Liposome-Based Multimodal Contrast Agent For Computed Tomography And Magnetic Resonance Imaging. 8th Annual Symposium of the Canadian Society of Pharmaceutical Sciences (May 2005).
- Ho E., Allen C., Piquette-Miller M. In Vitro Characterization of a Novel Lipid- Polymer Implant System for the Combination Delivery of Paclitaxel and Carboplatin. 8th Annual Symposium of the Canadian Society of Pharmaceutical Sciences (May 2005).
- Vassileva V., Grant J., Allen C., Piquette-Miller M. In vivo Release Characterization of a Novel Implantable Paclitaxel Loaded Lipid Polymer System. 8th Annual Symposium of the Canadian Society of Pharmaceutical Sciences (May 2005).
- Lee H., Zeng F., Dunne M., Allen C. Poly(d-valerolactone)-block-Methoxy Poly(ethylene glycol) Copolymers for Formulation of Hydrophobic Drugs. 8th Annual Symposium of the Canadian Society of Pharmaceutical Sciences (May 2005).
- Vassileva V., Grant J., Allen C., Piquette-Miller M. Novel Implantable Delivery System Increases Maximum Tolerable Doses of Paclitaxel in Mice. American Association for Cancer Research Annual Meeting (April 2005).
- Perkins G., Zheng J., Brock K., Allen C., Jaffray D. Nanoengineered multimodal contrast agent for medical image guidance. International Society of Optical Engineering Medical Imaging (February 2005).
- Ho E., Allen C., Piquette-Miller M. Preclinical Evaluation of a Novel 2-in-1 Drug Delivery Strategy for the Treatment of Ovarian Cancer. American Association of Pharmaceutical Scientists (November 2004).
- Vassileva V., Allen C., Piquette-Miller M. Release Profile Characterization of a Novel Implantable Paclitaxel Loaded Lipid Polymer System in CD-1 Mice. American Association of Pharmaceutical Scientists (November 2004).
- Grant J., Piquette-Miller M., Allen C. Characterization of Chitosan and Egg Phosphatidylcholine Films for Regional Delivery of Paclitaxel. Delivery Of Macromolecules Into Cells Using Non-Viral Vectors - IUBMB Symposium (July 2004).
- Liu J., Xiao Y., Ma C., Allen C. Design of Novel Biocompatible, Biodegradable Materials Based on Consideration of Polymer-Drug Miscibility. Delivery Of Macromolecules Into Cells Using Non-Viral Vectors - IUBMB Symposium (July 2004).
- Zeng F., Liu J., Allen C. Biodegradable Poly(ethylene glycol)-b-poly(5-benzyloxy-trimethylene carbonate) Copolymer Micelles for Drug Delivery. Delivery Of Macromolecules Into Cells Using Non-Viral Vectors - IUBMB Symposium (July 2004).
- Buck S., Khorasanirad Z., Leung G., Chen Y. L., Pennefather P., Allen C. Optimization of Processing Parameters in Suspension Polymerization to Produce Monodisperse Populations of Hydrogel Beads. 39th IUPAC Congress and 86th Conference of the Canadian Society for Chemistry (August 2003).
- Perkins G., Buck S., Damianovich A., Allen C., Jaffray D.A. Nanoengineered Lipid-Based Systems for Multimodality Imaging: Rational Design and Preliminary In-VitroCharacterization. World Congress of Medical Physics and BioEngineering (August 2003).
- Liu J., Xiao Y., Allen C. Use of Physico-Chemical Methods To Design a Block Copolymer-Based Formulation for the Anticancer Drug Ellipticine. Canadian Society of Pharmaceutical Sciences Annual Symposium (May 2003).
- Grant J., Allen C. Development and Physico-Chemical Characterization of a Polymer-Lipid Hydrogel Implant for Drug Delivery. Canadian Society of Pharmaceutical Sciences Annual Symposium (May 2003).
- Soo P.L., Terreau O., Savic R., Allen C., Maysinger D., Eisenberg A. Controllable design of block copolymer vehicles for drug delivery. American Chemical Society (August 2000).
- Allen C., Mrsic J., Kucic N., Eisenberg A., Maysinger D. Polycaprolactone-b-poly(ethylene oxide) Micelle -Incorporated FK506 Provides Rescue in the Peripheral Nervous System.Neuroscience Meeting (1999).
- Zhang L., Allen C., Yu K., Bartels C., Shen H., Maysinger D., Eisenberg A. Nanoengineered Aggregates of Various Architectures by Controlled Self-Assembly of Asymmetric Amphiphilic Diblock Copolymers in Solution. Polymer Preprints (1998).