Christine Allen is a Professor and the GlaxoSmithKline Chair in Pharmaceutics and Drug Delivery in the Leslie Dan Faculty of Pharmacy at the University of Toronto. She previously served as the Associate Dean Graduate Education and as the Associate Dean Academic. Her research is focused on the rational design and development of new materials and technologies for the delivery of drugs and contrast agents. Allen completed her doctoral research in the Department of Chemistry at McGill University and post-doctoral research in the Department of Advanced Therapeutics at the B.C. Cancer Agency. She joined University of Toronto in 2002, from Celator Pharmaceuticals Inc. (Vancouver, B.C.) where she had worked as a scientist and Assistant Director of materials research. She has over 100 peer-reviewed publications, numerous patent applications, and nine book chapters on both lipid and polymer-based delivery systems. She has served on several peer review panels for granting agencies including CIHR, NCIC and NIH. She was awarded a CIHR-Rx&D Career Award (2004-2009) for her research on the design and development of technologies for cancer treatment in addition to many other awards . Read more...
- Dunne M., Dou YN., Drake DM., Spence T., Gontijo SML., Wells PG., Allen C. Hyperthermia-Mediated Drug Delivery Induces Biological Effects at the Tumor and Molecular Levels that Improve Cisplatin Efficacy in Triple Negative Breast Cancer. Journal of Controlled Release. 2018, 282: 35-45. PubMed link
- Alhamami M., Cheng W., Lyu Y., Allen C., Zhang X., Cheng H. Manganese-Porphyrin-Enhanced MRI for the Detection of Cancer Cells: A Quantitative In Vitro Investigation with Multiple Clinical Subtypes of Breast Cancer. PLoS ONE. 2018, 13(5): e0196998. PubMed link
- Le Devedec F., Boucher H., Dubins DN, Allen C. Factors Controlling Drug Release in Cross-linked Poly(valerolactone) Based Matrices. Molecular Pharmaceutics. 2018, 15(4): 1565-1577. PubMed link
- Eetezadi S., Evans J., Shen Y., De Souza R., Piquette-Miller M., Allen C. Ratio-Dependent Synergism of a Doxorubicin and Olaparib Combination in 2D and Spheroid Models of Ovarian Cancer. Molecular Pharmaceutics. 2017, 15(2) 472-485. PubMed link
- Dunne M., Hynynen K., Allen C. Thermosensitive Nanomedicines Could Revolutionize Thermal Therapy in Oncology. Nanotoday. 2017, 16: 9-13. ScienceDirect link